Let's Get Lupus Facts Straight!

Television show ‘Good Wife’ conveys misinformation about lupus

New York, NY—The S.L.E. Lupus Foundation was thrilled to hear “lupus” on last week’s season premiere of the CBS show, “The Good Wife”—but also dismayed to hear that misinformation about the disease was being communicated.

The episode indicated that the autoimmune disease (or medicines taken for it) could change a person's blood type, such as from a group O to a group AB blood type.

Misinformation on Lupus

“What was implied on the show is incorrect,” said Ellen Ginzler, MD, M.P.H, a rheumatologist with a large lupus practice at State University of New York Downstate Medical Center (SUNY). “Lupus and the medicines taken for the disease cannot change a person’s blood type.”

“In 20 years at SUNY and Kings County Hospital Center (KCHC), I don't remember a lupus patient for whom the blood bank had a real problem in determining ABO [blood] type, despite having tested many with auto-antibodies,” added Elizabeth S. Gloster, MD, blood bank director at SUNY and KCHC and a professor of clinical pathology.

“Moreover, I have never heard of a real change in ABO type in lupus patients—i.e., a structural change in ABO antigens that would be reflected as a change in ABO type,” said Dr. Gloster.

Importance of Getting the Facts Straight

Lupus is a serious and potentially fatal chronic illness in which the immune system mistakenly attacks otherwise healthy tissues and organs.

Accurate information and experienced care are vital for proper diagnosis, treatment, and prevention of further damage in lupus, which affects approximately 1.5 million Americans and millions more worldwide.

For factual information about lupus, see our “About Lupus” section.

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Comments

well read this then somebody didn't do the homework

The Lancet, Volume 369, Issue 9557, Pages 186 - 187, 20 January 2007

doi:10.1016/S0140-6736(07)60099-3Cite or Link Using DOIChange in blood group in systemic lupus erythematosus Search Results for Ingeborg M Bajema in The Lancet •Change in blood group in systemic lupus erythematosus Idske CL Kremer Hovinga a, Marije Koopmans a, Emile de Heer a, Jan A Bruijn a, Ingeborg M Bajema a A transient blood group change from A to AB in a 26-year-old woman presenting with systemic lupus erythematosus (SLE), was interpreted by Norio Nakamura and colleagues (Sept 16, p 1022)1 as being the result of agglutinin to anti-B antibodies, and therefore, essentially, as a false-positive result. Blood group changes have been reported in leukaemia2 and stem-cell transplantation,3 but to our knowledge never before in an autoimmune disease such as SLE. However, more than 30 years ago, Ottensooser and colleagues reported that, in 45 patients with SLE, the frequency of blood groups B and AB exceeded that of controls, the difference reaching twice the standard error.4 This finding is possibly linked to that of Nakamura and colleagues, irrespective of whether the test results are true or false. this is just an abstract read the whole thing!!!